Here is list of all lab peer-reviewed research articles, publications, and abstracts, which highlights the cutting-edge research our lab is doing in health disparities.

(Last Updated: March 24, 2023)

For a complete list of publications, please click here.


  1. Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene. Br J Cancer, 2023 Pubmed
  2. Advancing gastric cancer precision medicine with novel genomic screens. J Pathol, 2023 Pubmed
  3. Colorectal Cancer Risk and Ancestry in Colombian admixed Population. medRxiv 2023. medRxiv


  1. Cancer screening and breast cancer family history in Spanish-speaking Hispanic/Latina women in California. Frontiers Oncology, 2022 Pubmed
  2. Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Patients with Myeloma? Cancer Epidemiol Biomarkers Prev. 2022 Pubmed
  3. A Cancer Health Needs Assessment Reveals Important Differences Between US-Born and Foreign-Born Latinos in California. Frontiers Oncology, 2022 Pubmed
  4. Recombination events drives the emergence of Colombian Helicobacter pylori subpopulations with self-identity ancestry. Virulence, 2022 Pubmed
  5. A repository of PDX histology images for exploring spatial heterogeneity and cancer dynamics. Cancer Research, 2022 Abstract
  6. Elucidating arsenic dependent carcinogenesis in humans. Cancer Research, 2022 Abstract
  7. Identification of predisposition and progression gastric cancer biomarkers in Latinos. Cancer Research, 2022 Abstract
  8. Preclinical studies of chemotherapies and targeted therapies to address gastric cancer disparities. Cancer Research, 2022 Abstract
  9. Identification of optimal set of genetic variants from a previously reported polygenic risk score for breast cancer risk prediction in Latin American women. Cancer Research, 2022 Abstract
  10. Addressing cancer health disparities among US minority populations with patient-derived xenografts. Cancer Research, 2022 Abstract
  11. CDH1 and CTNNA1 variants with incomplete penetrance in hereditary gastric cancer Chilean families. Cancer Research, 2022 Abstract
  12. Association between the consumption of meat and carbonated drinks and early onset gastric cancer in Chilean patients. Cancer Research, 2022 Abstract
  13. Establishing and characterizing patient derived models from racial/ethnic minority gastric cancer patients to advance cancer precision health equity. Cancer Research, 2022 Abstract
  14. Functional modeling and characterization of high frequency mutations associated with gastric cancer in US racial and ethnic minority populations. Cancer Research, 2022 Abstract
  15. Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Myeloma Patients? Cancer Epidemiology, Biomarkers & Prevention, 2022 Pubmed
  16. PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery. NAR Cancer, 2022 Pubmed
  17. Diversifying preclinical research tools: expanding patient-derived models to address cancer health disparities. Trends in Cancer, 2022 Pubmed
  18. Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nature Communications, 2022 Pubmed
  19. Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nature Communication, 2022 Pubmed


  1. Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature Genetics, 2021 Pubmed
  2. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature Genetics, 2021 Pubmed
  3. The dual pandemic of COVID-19 and systemic inequalities in US Latino communities. Cancer, 2021 Pubmed
  4. Cancer health disparities in racial/ethnic minorities in the United States. British Journal of Cancer, 2021 Pubmed


  1. Haplotype analysis of the internationally distributed BRCA1 c.3331_3334delCAAG founder mutation reveals a common ancestral origin in Iberia. Breast Cancer Research, 2020 Pubmed
  2. The Genetic Population Structure of Robinson Crusoe Island, Chile. Frontiers Genetics, 2020 Pubmed
  3. Genome Sequences of Three Colombian Helicobacter pylori Strains Isolated from Tolimense Patients. Microbiology Resource Announcements, 2020 Pubmed
  4. Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women. Cancer Research, 2020 Pubmed


  1. Molecular Subtypes and Driver Mutations in Latinos with Gastric Cancer: Implications for Etiological and Translational Research. Advancing the Science of Cancer in Latinos, 2019 Pubmed
  2. Editorial: Accomplishments, Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition. Frontiers in Oncology, 2019 Pubmed
  3. A polygenic risk score for breast cancer in U.S. Latinas and Latin-American women. Journal of the National Cancer Institute, 2019 Pubmed
  4. BRAF and TERT mutations in papillary thyroid cancer patients of Latino ancestry. Endocrine Connections, 2019 Pubmed
  5. Racial/ethnic differences in survival among gastric cancer patients in California. Cancer Causes and Control, 2019 Pubmed
  6. Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer’s Disease Center. Journal of Alzheimers Disease, 2019 Pubmed
  7. Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas. Breast Cancer Research, 2019
  8. Subtypes and Driver Mutations in Latinos with Gastric Cancer: Implications for Etiological and Translational Research. Advancing the Science of Cancer in Latinos, 2019 Springer


  1. Resolving gastric cancer aetiology: an update in genetic predisposition. Lancet Gastroenterology and Hepatology, 2018 Pubmed
  2. Moving the needle on colorectal cancer genetics: it takes more than two to TANGO British Journal of Cancer, 2018 Pubmed
  3. Progress and future challenges in again and diversity research in the United States Alzheimer’s & Dementia, 2018 Pubmed
  4. Native American gene community to the modern admixed population from the Colombian Andes: Implication for biomedical, population and forensic studies FSI Genetics, 2018 Pubmed
  5. PALB2 as a familial gastric cancer gene: is the wait over? Gastroenterology & Hepatology, 2018 Pubmed


  1. Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance. Scientific Reports 2017 Pubmed
  2. BRCA1 and BRCA2 founder mutaitons account for 78% of germline carriers among hereditary breast cancer families in Chile Oncotarget, 2017 Pubmed


  1. Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer. Gastroenterology, 2016 Pubmed
  2. Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia. Medicine (Baltimore), 2016 Pubmed
  3. Clinical features of Hispanic thyroid cancer cases and the role of known genetic variants on disease risk. Medicine (Baltimore), 2016 Pubmed
  4. RE: HABP2 G534E mutation in familial nonmedullary thyroid cancer. Journal of the National Cancer Institute, 2016 Pubmed
  5. The hunting of the snark: whither genome-wide association studies for colorectal cancer? Gastroenterology, 2016 Pubmed
  6. The HABP2 G534E polymorphism does not increase nonmedullary thyroid cancer risk in Hispanics. Endocrine Connections, 2016 Pubmed


  1. The HABP2 G534E variant is an unlikely cause of familial non-medullary thyroid cancer. Journal of Clinical Endocrinology and Metabolism, 2015. Pubmed
  2. The 8q24 rs6983267G variant is associated with increased thyroid cancer risk. Endocrine Related Cancer, 2015 Pubmed


  1. Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics, 2014 Pubmed
  2. Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Human Genetics, 2014 Pubmed
  3. Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. Nature Communications, 2014 Pubmed


  1. Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study. Clinical Cancer Research, 2013 Pubmed
  2. Much of the population genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas. Gastroenterology, 2013 Pubmed


  1. Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nature Genetics 2012  Pubmed
  2. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nature Genetics, 2012 Pubmed See also
  3. Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24. Journal of Medical Genetics. 2012 Pubmed PMC Full text


  1. Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11 refines regional association signals and in silico analyses suggests functional variation and identifies unexpected candidate target genes. Human Molecular Genetics, 2011 Pubmed PMC Full text
  2. The GREM1, BMP4 and BMP2 loci harbor multiple common susceptibility variants for colorectal cancer. PLOS Genetics, 2011 Pubmed PMC Full text


  1. Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nature Genetics, 2010 Pubmed
  2. Genetic dissection of intermediate phenotypes as a way to discover novel cancer susceptibility alleles. Current Opinions in Genetics and Development, 2010 Pubmed
  3. Challenges in the identification and use of rare disease-associated predisposition variants. Current Opinions in Genetics and Development, 2010 Pubmed
  4. Comprehensive assessment of variation at the Transforming Growth Factor Beta Type I Receptor locus and colorectal cancer predisposition. Proceedings of the National Academy of Science USA, 2010 Pubmed PMC Full text


  1. The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nature Genetics, 2009 Pubmed See also
  2. Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK. Human Molecular Genetics, 2009 Pubmed Free Fulltext


  1. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nature Genetics, 2008 Pubmed
  2. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics, 2008 Pubmed PMC Full text
  3. Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nature Genetics, 2008 Pubmed


  1. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nature Genetics, 2007 Pubmed
  2. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nature Genetics, 2007 Pubmed See also


  1. Strong Amerind/white sex bias and a possible Sephardic contribution among the founders of a population in northwest Colombia. American Journal of Human Genetics, 2000 Pubmed PMC Full text Research Highlight Editorial (Pubmed) Editorial (PMC Full text)